An allosteric modulator to control endogenous G protein-coupled receptors with light

Journal article

S. Pittolo, X. Gomez-Santacana, K. Eckelt, Xavier Rovira, J. Dalton, Cyril Goudet, Jean-Philippe Pin, A. Llobet, J. Giraldo, Amadeu Llebaria, …

Nature Chemical Biology, Vol.10(10), pp.813--5

10/2014

Abstract

Humans

Animals

HEK293 Cells

Rats

Primary Cell Culture

Gene Expression

Transfection

Allosteric Site

Allosteric Regulation/radiation effects

Newborn

Astrocytes/cytology/drug effects/metabolism/radiation effects

Azo Compounds/*chemistry

inhibitors/genetics/*metabolism

Larva/drug effects/physiology/radiation effects

Light

Photochemical Processes

Pyridines/chemical synthesis/*pharmacology

Receptor

Metabotropic Glutamate 5/agonists/antagonists &

Recombinant Proteins/chemistry/genetics

Xenopus/physiology

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Title: An allosteric modulator to control endogenous G protein-coupled receptors with light
Creators - without role: S. Pittolo - Institute for Bioengineering of Catalonia
X. Gomez-Santacana - Institute for Bioengineering of Catalonia
K. Eckelt - Institute for Bioengineering of Catalonia
Xavier Rovira - Université de Montpellier, Institut de Génomique Fonctionnelle - IGF
J. Dalton
Cyril Goudet - Université de Montpellier, Institut de Génomique Fonctionnelle - IGF
Jean-Philippe Pin - Université de Montpellier, Institut de Génomique Fonctionnelle - IGF
A. Llobet - Institut d'Investigació Biomédica de Bellvitge
J. Giraldo - Universitat Autònoma de Barcelona
Amadeu Llebaria - Institute of Advanced Chemistry of Catalonia
P. Gorostiza - Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine
Publication Details: Nature Chemical Biology, Vol.10(10), pp.813--5
Identifiers: 9944588309311
Academic Unit: Institut de Génomique Fonctionnelle - IGF
Language: English
Resource Type: Journal article
Local Fields: hal-01942934