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Addressing the scope of the azide-nitrile cycloaddition in glycoconjugate chemistry. The assembly of C-glycoclusters on a calix[4] arene scaffold through tetrazole spacers
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Addressing the scope of the azide-nitrile cycloaddition in glycoconjugate chemistry. The assembly of C-glycoclusters on a calix[4] arene scaffold through tetrazole spacers

Alessandro Dondoni et Alberto Marra
Tetrahedron, Vol.63(27), pp.6339-6345
02/07/2007

Résumé

Chemistry Chemistry, Organic Physical Sciences Science & Technology
New glycoclusters constituted of ribosylmethyl, galactosylmethyl, and glucosylmethyl fragments assembled on a calix[ 4] arene platform by means of propoxytetrazole spacers have been prepared by coupling the corresponding sugar azides with p-toluenesulfonyl cyanide, and then reacting 1-glycosylmethyl-5-sulfonyl-tetrazole derivatives thus formed with a calix[ 4] arene tetrol. (c) 2007 Elsevier Ltd. All rights reserved.

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