Résumé
Objectives: To evaluate the Sentinel-PETIA cystatin C on Architect c8000 (R) analyzer.
Design and methods: We assessed analytical performances and clinical relevance by comparison with a reference isotopic method in kidney transplant recipients.
Results: This assay exhibited reliable precision and was close to the non standardized Siemens-PENIA method. All tested equations allowed reliable assessment of GFR.
Conclusions: Cystatin C improved GFR determination at the critical level of 60 mL/min/1.73 m(2). New formulas might be necessary after IFCC standardization. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.