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A tandem aza-Friedel-Crafts reaction/Hantzsch cyclization: a simple procedure to access polysubstituted 2-amino-1,3-thiazoles
Journal article   Peer reviewed

A tandem aza-Friedel-Crafts reaction/Hantzsch cyclization: a simple procedure to access polysubstituted 2-amino-1,3-thiazoles

Guilhem Chaubet, Ludovic T. Maillard, Jean Martinez and Nicolas Masurier
Tetrahedron, Vol.67, pp.4987-4904
2011

Abstract

aza-FriedeleCrafts reaction Hantzsch cyclization 2-Amino-1 3-thiazoles Imidazo[1 2-a]pyridine
A tandem aza-FriedeleCrafts reaction/Hantzsch cyclization is described to access various polysubstituted 2-amino-1,3-thiazoles from electron-rich (hetero)-aromatic rings, aldehydes, thiourea and a-chloroketones.
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