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A stereocontrolled approach towards highly oxygenated taxane C and CD-ring precursors
Article de revue   Avec comité de lecture

A stereocontrolled approach towards highly oxygenated taxane C and CD-ring precursors

Jean-Pierre Uttaro, Gérard Audran, Jean-Marie Galano et Honoré Monti
Tetrahedron letters, Vol.43(15), pp.2757-2760
08/04/2002

Résumé

domino reaction stereoselective epoxidation stereoselective reaction synthesis taxoids
Based upon a remarkable β-face diastereoselection, a stereocontrolled construction of bicyclic systems with the appropriate stereochemical disposition of the substituents belonging either to a Baccatin-I C-ring precursor or a Taxol® CD-ring precursor is reported. A stereocontrolled approach of Baccatin-I C-ring precursor or Taxol® CD-ring precursor is reported.

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