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A prospective study of hormone therapy and depression in community-dwelling elderly women: the three city study.
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A prospective study of hormone therapy and depression in community-dwelling elderly women: the three city study.

Jacqueline Scali, Joanne Ryan, Isabelle Carrière, Jean-François Dartigues, Béatrice Tavernier, Karen A. Ritchie et Marie-Laure Ancelin
Journal of Clinical Psychiatry, Vol.71(12), pp.1673-9
12/2010
DOI: https://doi.org/10.4088/JCP.09m05188blu
PMID: 20816026

Résumé

transdermal progestogen postmenopausal estradiol Depression Administration, Cutaneous Aged Progesterone Congeners Prospective Studies Aged, 80 and over Risk Factors Drug Therapy, Combination Estradiol Estrogen Replacement Therapy Estrogens Female France Follow-Up Studies Humans Incidence Logistic Models Medication Adherence Multivariate Analysis Odds Ratio Postmenopause
Hormone therapy was not associated with a protective effect against the emergence of depressive symptoms in elderly postmenopausal women. However, discontinuing treatment could increase the risk of depressive symptoms. Data on the appropriate management of depression in the context of HT discontinuation among postmenopausal women require further investigation.

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