Abstract
Wanted! A new lasso molecular shuttle was synthesized by a self-entanglement strategy. In their Full Paper on page 2982 ff., F. Coutrot et al. describe the efficient preparation of a new lasso molecular switch containing an anilinium template. Trapping of the BMP25C8 macrocycle was achieved by benzylation of the triazole moiety and allowed the isolation of a bi-stable lasso molecular switch, in which benzyltriazolium acts as a gate and a molecular station at the same time. Variation of pH triggered the tightening and loosening of the lasso.