A new way to silicone-​based peptide polymers

Said Jebors; Jeremie Ciccione; Al Halifa Soultan; Benjamin Nottelet; Christine Enjalbal; Céline M'Kadmi; Muriel Amblard; Ahmad Mehdi; Jean Martínez; Gilles Subra

doi:10.1002/anie.201411065

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A new way to silicone-based peptide polymers

Journal article

Open access

Peer reviewed

A new way to silicone-based peptide polymers

Said Jebors, Jeremie Ciccione, Al Halifa Soultan, Benjamin Nottelet, Christine Enjalbal, Céline M'Kadmi, Muriel Amblard, Ahmad Mehdi, Jean Martínez and Gilles Subra

Angewandte Chemie, Vol.54(12), pp.3778-3782

2015

DOI: https://doi.org/10.1002/anie.201411065

PMID: 25650781

Abstract

Biopolymers

Comb polymers

Dimers

Hybrid peptides

Siloxane bonds

Amino Acid Sequence

Cholecystokinin

Peptides

Protein Binding

Silanes

Silicones

Water

We describe a new class of silicone-containing peptide polymers obtained by a straightforward polymerization in water using tailored chlorodimethylsilyl peptide blocks as monomeric units. This general strategy is applicable to any type of peptide sequences, yielding linear or branched polymer chains composed of well-defined peptide sequences.

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Title: A new way to silicone-based peptide polymers
Creators - without role: Said Jebors - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Jeremie Ciccione - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Al Halifa Soultan - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Benjamin Nottelet - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Christine Enjalbal - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Céline M'Kadmi - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Muriel Amblard - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Ahmad Mehdi - Université de Montpellier, Institut Charles Gerhardt Montpellier - ICGM
Jean Martínez - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Gilles Subra - Université de Montpellier, Institut des Biomolécules Max Mousseron - IBMM
Publication Details: Angewandte Chemie, Vol.54(12), pp.3778-3782
Identifiers: 9942656109311
Academic Unit: Institut Charles Gerhardt Montpellier - ICGM; Institut des Biomolécules Max Mousseron - IBMM
Language: English
Resource Type: Journal article
Local Fields: hal-01206458