A multicenter randomized controlled trial of a 3-L/kg/min versus 2-L/kg/min high-flow nasal cannula flow rate in young infants with severe viral bronchiolitis (TRAMONTANE 2)

Christophe Milesi; Anne-Florence Pierre; Anna Deho; Robin Pouyau; Jean-Michel Liet; Camille Guillot; Anne-Sophie Guilbert; Jérôme Rambaud; Astrid Millet; Mickael Afanetti; Julie Guichoux; Mathieu Genuini; Thierry Mansir; Jean Bergounioux; Fabrice Michel; Marie-Odile Marcoux; Julien Baleine; Sabine Durand; Philippe Durand; Stéphane Dauger; Etienne Javouhey; Stéphane Leteurtre; Olivier Brissaud; Sylvain Renolleau; Aurélie Portefaix; Aymeric Douillard; Gilles Cambonie; For The Gfrup Respiratory Study Group For The Gfrup Respiratory Study Group

doi:10.1007/s00134-018-5343-1

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A multicenter randomized controlled trial of a 3-L/kg/min versus 2-L/kg/min high-flow nasal cannula flow rate in young infants with severe viral bronchiolitis (TRAMONTANE 2)

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A multicenter randomized controlled trial of a 3-L/kg/min versus 2-L/kg/min high-flow nasal cannula flow rate in young infants with severe viral bronchiolitis (TRAMONTANE 2)

Christophe Milesi, Anne-Florence Pierre, Anna Deho, Robin Pouyau, Jean-Michel Liet, Camille Guillot, Anne-Sophie Guilbert, Jérôme Rambaud, Astrid Millet, Mickael Afanetti, …

Intensive Care Medicine, Vol.44(11), pp.pp. 1870-1878

01/01/2018

DOI: https://doi.org/10.1007/s00134-018-5343-1

Abstract

BRONCHIOLITIS

HIGH-FLOW NASAL CANNULA

INFANT

NONINVASIVE VENTILATION

High-flow nasal cannula (HFNC) therapy is increasingly proposed as first-line respiratory support for infants with acute viral bronchiolitis (AVB). Most teams use 2 L/kg/min, but no study compared different flow rates in this setting. We hypothesized that 3 L/kg/min would be more efficient for the initial management of these patients.

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Title: A multicenter randomized controlled trial of a 3-L/kg/min versus 2-L/kg/min high-flow nasal cannula flow rate in young infants with severe viral bronchiolitis (TRAMONTANE 2)
Creators - without role: Christophe Milesi - Hôpital Arnaud de Villeneuve
Anne-Florence Pierre - Bicêtre Hospital
Anna Deho - Hôpital Robert-Debré
Robin Pouyau - Hospices Civils de Lyon
Jean-Michel Liet
Camille Guillot - Hôpital Jeanne de Flandre
Anne-Sophie Guilbert - Hôpital d'Hautepierre
Jérôme Rambaud - Hôpital Armand-Trousseau
Astrid Millet - Université Grenoble Alpes
Mickael Afanetti - Fondation Lenval
Julie Guichoux
Mathieu Genuini
Thierry Mansir - Centre Hospitalier De Pau
Jean Bergounioux - Hôpital Raymond-Poincaré
Fabrice Michel
Marie-Odile Marcoux - Université de Toulouse
Julien Baleine - Hôpital Arnaud de Villeneuve
Sabine Durand - Hôpital Arnaud de Villeneuve
Philippe Durand - Bicêtre Hospital
Stéphane Dauger - Hôpital Robert-Debré
Etienne Javouhey - Hospices Civils de Lyon
Stéphane Leteurtre - Hôpital Jeanne de Flandre
Olivier Brissaud
Sylvain Renolleau
Aurélie Portefaix - Inserm
Aymeric Douillard - Hôpital Arnaud de Villeneuve
Gilles Cambonie - Hôpital Arnaud de Villeneuve
For The Gfrup Respiratory Study Group For The Gfrup Respiratory Study Group
Publication Details: Intensive Care Medicine, Vol.44(11), pp.pp. 1870-1878
Identifiers: 9940161509311
Academic Unit: Université de Montpellier
Language: English
Resource Type: Journal article
Local Fields: hal-02050422