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A human induced pluripotent stem cell-based modular platform to challenge sensorineural hearing loss
Journal article   Open access

A human induced pluripotent stem cell-based modular platform to challenge sensorineural hearing loss

Azel Zine, Yassine Messat and Bernd Fritzsch
STEM CELLS
08/01/2021

Abstract

The sense of hearing depends on a specialized sensory organ in the inner ear, called the cochlea, which contains the auditory hair cells (HCs). Noise trauma, infections, genetic factors, side effects of ototoxic drugs (ie, some antibiotics and chemotherapeutics), or simply aging lead to the loss of HCs and their associated
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