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A genetic programme for neuronal connectivity.
Journal article   Peer reviewed

A genetic programme for neuronal connectivity.

A. Ghysen and C. Dambly-Chaudière
Trends in Genetics, Vol.16(5), pp.221-6
05/2000
PMID: 10782116

Abstract

Animals Axons Drosophila Gene Expression Regulation, Developmental Mutation Neurons Neurons, Afferent Sense Organs
What is the nature of the genetic programme that allows neurons to extend their axons and connect to other neurons with a high degree of specificity? Work on the sensory neurons of the fly has shown how the control of neuronal identity is embedded in the general developmental programme of the organism. The ongoing analysis of pathfinding mutants suggests plausible mechanisms for the translation of neuronal identity into axonal behaviour.
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