Abstract
The study of nucleoside and nucleotide analogs has been the subject of extensive development during these last decades. In this field, additions or substitutions on the sugar residue had led to potent drugs in antiviral and anticancer chemotherapies. Herein, we reported the stereoselective synthesis of a new series of pyrimidine nucleosides bearing a double modification in the 2’ and 3’ positions of the sugar scaffold.