2′-Deoxy-2′-C-trifluoromethyl β-D-Ribonucleoside Analogues: Synthesis and Antiviral Evaluations

Frédéric Jeannot; Gilles Gosselin; Christophe Mathé

doi:10.1081/NCN-120022671

Retour

2′-Deoxy-2′-C-trifluoromethyl β-D-Ribonucleoside Analogues: Synthesis and Antiviral Evaluations

Article de revue

Avec comité de lecture

2′-Deoxy-2′-C-trifluoromethyl β-D-Ribonucleoside Analogues: Synthesis and Antiviral Evaluations

Frédéric Jeannot, Gilles Gosselin et Christophe Mathé

Nucleosides, nucleotides & nucleic acids, Vol.22(5-8), pp.857-859

01/10/2003

DOI: https://doi.org/10.1081/NCN-120022671

PMID: 14565296

Résumé

2′-Deoxy-2′-C-trifluoromethyl

Antiviral evaluations

D-Ribonucleosides

Hitherto unknown 2′-deoxy-2′-C-trifluoromethyl- β -D-ribonucleoside derivatives bearing the five naturally occurring nucleic acid bases have been synthesized. The compounds were tested for their activity against HIV, HBV and several RNA viruses, but they did not show significant antiviral effect.

Indicateurs

1 Consultations de la notice

Détails

Titre: 2′-Deoxy-2′-C-trifluoromethyl β-D-Ribonucleoside Analogues: Synthesis and Antiviral Evaluations
Créateurs - sans rôle: Frédéric Jeannot - Laboratoire de Chimie Organique Biomoléculaire de Synthèse
Gilles Gosselin - Laboratoire Coopératif Idenix , Université Montpellier II
Christophe Mathé - Université de Montpellier
Détails de publication: Nucleosides, nucleotides & nucleic acids, Vol.22(5-8), pp.857-859
Éditeur: Taylor & Francis Group
Nombre de pages: 3
Identifiants: 99138891909311
Unité académique: Institut des Biomolécules Max Mousseron - IBMM
Langue: English
Type de ressource: Journal article