Résumé
Since the 2000s, advances in onco-hematology have led to the emergence of oral targeted therapies, which improve the survival of cancer patients and are administered on an outpatient basis. This development poses challenges in terms of side-effects and compliance with treatment, which are poorly understood by front-line healthcare professionals. Multidisciplinary initiatives have been put in place to improve monitoring of adverse effects, but coordination remains inadequate. General practitioners, who are becoming increasingly involved, lack visibility of these treatments, so communication needs to be stepped up to optimise the management of patients on oral targeted therapies. This thesis aims to identify the needs of general practitioners in the Occitanie region in order to improve coordination with hematologists. This prospective descriptive observational study was carried out in 2024 among general practitioners in the Occitanie region. Doctors were contacted by email via the departmental councils of the Order of Physicians in six departments, soliciting 4,375 practitioners (53.4% of GPs in the region). A total of 63 responses were received (response rate of 1.44%). Data were collected using a Microsoft Forms Office 365 questionnaire, comprising 6 questions and a free text section, and analysed as percentages. The study received 63 responses. The majority of doctors (83%) followed patients on chemotherapy and targeted therapy, while 76% managed fewer than 5 patients on targeted therapy. Only 34% felt involved in the management of these patients, and of these, 56% would have liked more involvement. A majority (97%) expressed the need for more information, preferring information leaflets (56%). The open-ended responses showed a need for documents on protocols and adverse effects, and the importance of making better use of digital tools for coordinating care. The study was limited by a low response rate, due to restrictions on the distribution of the questionnaire. Despite these limitations, it reveals specific needs and suggests improvements to strengthen coordination between inpatient and outpatient care and improve patient management.