Résumé
The intestinal microbiota, along with other body microbiota, have captured the attention of numerous scientists. Their composition and variations continue to be poorly understood, and clinical implications remain limited. Probiotics are emerging as modulators, generating debates, andrecommendations concerning them are scarce. The proliferation of available products complicates potential studies and poses challenges for physicians. In this context, what are the practices of physicians in the field? Methods: a quantitative study in the form of an online questionnaire assessed the characteristics, knowledge, and prescription habits regarding probiotics of general practitioners and gastroenterologists practicing inFrance. Results: a total of 668 participants, including 585 general practitioners and 83 hepatogastroenterologists, were included. Among general practitioners, 20% never prescribe probiotics, while 35% prescribe them at least once a week. Key indications include post-antibiotic diarrhea, vaginal flora imbalances, and irritable bowel syndrome. Ultralevure© is widely prescribed, followed by less-studied combinations. Discussion: prescription frequency varies significantly. Physicians' knowledge in this field is limited, which acts as a major barrier to prescription. The quality of knowledge sources also varies. Less-studied mixtures are available in pharmacies, overshadowing more researched strains. Conclusion: despite limitedevidence, probiotics are extensively used, underscoring the need for comprehensive medical education. Biotherapeutic Live Products represent a promising evolution.