Résumé
The rational prescription and dispensing of PPIs is a major public health issue. Nearly a quarter of the French population was concerned in 2019 by the prescription of PPIs. These latter drugs are prescribed unnecessarily in 80% (source HAS) of cases of co-prescription of a PPI with an NSAID. However, PPIs can have serious side effects when taken over the long term.To explore these bibliographical results and identify courses of action for a more rational use of PPIs, I conducted a study to obtain the vision of the three people most involved in the prescription of a PPI: the patient, the doctor and pharmacist.The main result obtained is that each of these actors holds a share of responsibility in this overconsumption of PPIs and that they each have a role to play in the deprescription of PPIs.The pharmacist could play a key role in this collective approach, both for informing the patient about the adverse effects and the conditions for taking these drugs and for triggering a reflection on the part of the patient with his doctor when the treatment is prolonged beyond the initial duration of 8 weeks.