Résumé
The aim of this work was to explore the interaction between biomimetic supramolecular anddynamic constitutional chemistry ensembles and simple biological motifs. Research wasperformed in the following areas of interest: carbohydrate-protein interaction, vesicles,bilayers, ion channels and membrane transport constituting three projects. Quartz crystalmicrobalance measurement was coupled with nanoparticle mass amplification forinvestigation of lectin-carbohydrate interaction showing high specificity and affinityenhancement through multivalency. Polyoxomolydates, nanoarchitectures which possess thepotential to form biomimetic ion channels were shown to spontaneously partition in lipidbilayers and mediate cation flux, additionally theses anionic nanoclusters demonstratedelectrostatic organisation on lipid bilayers which can be applied in hybrid materialdevelopment and investigation the demonstrated medicinal properties of polyoxomolybdates.Lastly a lectin occluding supported liquid membrane was developed to investigate transport ofa simple dynamic combinatorial library.