Abstract
The development of new agricultural practices based on principles of agroecology needs to analyze complex interactions between plants and their biotic and abiotic environments. Our ability to analyze and to decipher these multiple stresses requires, on the one hand, adopting a new conceptual framework such as phytobiome or extended phenotype, and on the other hand, coupling methodologies that make it possible to analyze the whole plant phenotype -or targeted organs -at different scales (metabolome, cell, composition and tissue structure). In this work, we propose to combine innovative approaches based on light-matter interactionswith more classical 'omics' approaches to assess the variability of durum wheat response to multiple stresses: biotic (Septoria)and abiotic (nutritional stress).