Abstract
This thesis is a part of general research for novel, cheap and eco-friendly methods for the valorization of some subtrates and for the synthesis of interesting molecules in various fields such as material, pharmaceutical and organic chemistry. The main goal is to create new C-C and C-heteroatom bonds with high selectivity by using transition metal-catalysts.In the first part, a copper-catalyzed alkenes difunctionnalization has been realized to afford oxazolidinone, which contains an interesting moiety present in various bioactive molecules.In the second part, novel pyridyl diketone ligands associated to a copper catalyst have been employed in ammonia arylation reaction. This system led the amination of aryl iodides and bromides in mild temperature conditions to afford aniline derivatives, valuable molecules for the material chemistry.In the third part, we developed copper-catalyzed hydrofunctionnalizations of allenes to create new C-C, C-O and C-P bonds. These methods afford selectively the allylic products, that could be valuable key intermediates in organic chemistry.The last part consists in the developement of a novel ruthenium complex to allow the direct phenol amination without any previous activation.Key-words : alkenes, aniline, copper, allenes, hydrofunctionnalization, phenol, ruthenium