Double emulsion generation and separation by microfluidic consecutive flow focusing

Benoît Charlot; N. Sanchez; P. Roux; S. Teixeira

doi:10.1109/DTIP.2014.7056673

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Double emulsion generation and separation by microfluidic consecutive flow focusing

Benoît Charlot, N. Sanchez, P. Roux et S. Teixeira

2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), pp.1-5

2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP) (Cannes, France, 01/04/2014–04/04/2014)

DOI: https://doi.org/10.1109/DTIP.2014.7056673

Résumé

This article describes the first developments of a microfluidic circuit for the continuous generation of monodisperse polymersomes. The generation of these vesicles is made in a consecutive flow focusing cross-junctions structure from non miscible fluids. The device allows generating a stream of polymersomes in two steps. The breaking of a focused water flow creates first water droplets in a solution of diblock polymer and then the double emulsion is generated at the second constriction. This paper will describe microflabrication of the device and a study of the dynamics of droplets formation by high frame rate videomicroscopy. The work has been done on liposome in first steps and them with Pb-b-PEO block polymer in a second time. Finally the paper will decribe the addition of a separation structure for sorting generated vesicles by their size.

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Détails

Titre: Double emulsion generation and separation by microfluidic consecutive flow focusing
Créateurs - sans rôle: Benoît Charlot - Université de Montpellier, Institut d'Electronique et des Systèmes - IES
N. Sanchez - Laboratoire d’Etudes du Rayonnement et de la Matière en Astrophysique et Atmosphères
P. Roux - Université Gustave Eiffel
S. Teixeira - Sanofi (France)
Détails de publication: 2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), pp.1-5
Colloque: 2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP) (Cannes, France, 01/04/2014–04/04/2014)
Identifiants: 9938612009311
Unité académique: Institut d'Electronique et des Systèmes - IES
Langue: English
Type de ressource: Conference proceeding
Champs locaux: hal-02091447