Résumé
Background: Dengue is a vector borne disease transmitted by Aedes mosquito species. The disease affects all major cities in South-east Asia. Urbanization of the world is a clear factor that led to Aedes and dengue spread during the past decades. In Lao PDR, two epidemics hit the country in 2010 and in 2013, affecting respectively more than 22,890 and 44,171 individuals. However, if some researches were conducted in some localities of Vientiane (Vallée and al, 2011), the overall dengue context and its geography are little known.This presentation has two aims: 1° to present dengue epidemiology and its geography in Vientiane Capital using surveillance system implemented by Institut Pasteur du Laos 2° to uncover what drives the dengue force of infection among built up, socio-economic, local temperature and more innovative data which allow to describe commuting pattern of millions of individuals.Methods and materials: To study the link between environmental disparities and incidence rate of cases, we rely on several data: (i) Global Human settlement, which allows to quantify the sprawl of built-up areas, (ii) surface temperature detected trough Landsat 8, (iii) census data which will help us to qualify the social economic disparities (iv) commuting patterns of Facebook users to understand the migration flow in the city and its link with dengue spread.Results: A total of 2699 cases were recorded and could be located at village level. The effect of village typology (i.e. urban core, 1st, 2nd peripheries and rural areas) on dengue incidence was investigated using a Poisson regression. We could underline that the main risk factors in Vientiane Capital are not linked with poverty but are associated with the percentage of individuals that recently migrated to the city. The second risk factor stands precisely in the degree of urban centrality of a village.Conclusion: This research suggest that risk factors do not only depend on the local context but are also impacted by the structure and intensity of connectivity between villages composing Vientiane Capital. This results underline that dengue could be better model by introducing mobility of individuals at city level.