Résumé
Plants need to adapt to a myriad of combined signals coming from i) their environment and ii) their own metabolism. Gene Regulatory Networks (GRNs) leading to these adaptations and signal integration are the central point of our research. Here, I will show that by focusing on Nitrate (NO3-) regulated transcription factors (TFs) and their genome wide activity, using a technique called TARGET (Transient Assay Reporting Genome wide Effect of Transcription factors), wewere able to identify several important signaling cross-talks between NO3-, Phosphate (PO43-) and Reactive Oxygen Species (ROS) pathways . These studies open perspectives at the same time on i) applied biotechnology [since we discovered genotypes with an enhanced NO3- transport activity], as well as on ii) basic understanding of large GRN function, dynamics, emerging properties, and topology in plants . These recent works will be presented and discussed aswell as a new kind of GWAS we have been “cooking" for a long time