Résumé
Foot ulcers are common in diabetic patients, with a cumulative incidence rate as high as 25%, and they frequently become infected. The spread of infection to soft tissue and to bone is a major causal factor for lower-limb amputation. For this reason, early diagnosis and appropriate treatment are essential, including treatment which is both local (of the foot) and systemic (metabolic) and this requires coordination by a multidisciplinary team. Optimal treatment also often involves extensive surgical debridement and management of the wound base, effective antibiotic therapy, consideration of revascularization and correction of metabolic abnormalities, such as hyperglycemia. The aim of this chapter is to review the different approaches to management, as well as recently published data, in order to help clinicians in the diagnosis, assessment and treatment of diabetic foot infections with appropriate antibiotic therapy.