Résumé
Brain biopsies are neurosurgical procedures that involve the sampling of a small portion of brain tissue for diagnostic purposes. These procedures are crucial for the diagnosis of neurological conditions including tumors, infections, inflammatory diseases, and neurodegenerative disorders. There are two main types of brain biopsy techniques: stereotactic and open. Stereotactic biopsies are best for targeting deep brain structures, small lesions, or areas near critical brain structures. These can be performed using stereotactic frames, neuronavigation assistance, or robotic assistance. Open biopsies are preferentially used when the lesion is superficial, leptomeningeal sampling is needed, or a larger sample size is required for definitive diagnosis. This chapter focuses on non-robotized brain biopsy techniques and outlines their technical aspects, key features, and applications.