Résumé
Aberrant glycosylations of proteins and lipids of cancer cells represent crucial structural elements for the development of antitumoral vaccines. Combining these tumor-associated carbohydrate antigens with carriers (e.g., protein or lipid) or with immunostimulant peptides enables glycoconjugates to stimulate immunity against tumors. In this chapter we describe the chemical strategies that are commonly used to prepare these two classes of semi-synthetic and fully synthetic antitumoral vaccines.